| FIT | Stool test | 76-95% | 27-47% | 89-96% | Weak | Low | No |
| FIT-DNA (Cologuard) | Stool test that uses FIT (see above) and fecal DNA | 93% | 43% | 85% | Emerging | Low | No |
| CT Colonography | CT scan after undergoing a bowel prep | 96% | 67-94% for > 10 mm and 73-98% for > 6 mm | 86-98% for > 10 mm and 80-93% for > 6 mm | Weak | Low | Yes |
| Flexible Sigmoidoscopy | Limited prep and limited endoscopic evaluation through the rectum | 58-75% | 72-86% | 92% | Strong | Intermediate | Partial |
| Colonoscopy | Endoscopic evaluation through the rectum | 95% | 89-98% for > 10 mm and 75-93% for > 6 mm | 90% | Intermediate | High | Yes |