The Crohn’s Disease Activity Index (CDAI) is a research tool to determine the current severity of Crohn’s disease.
Summation of factors and variables that are positive.
Explanation of Result :
CDAI < 150 is used as a marker of remission of Crohn’s
CDAI > 450 is a marker of severe disease
* Please verify all calculations prior to clinical use.
References
- Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn’s disease activity index. National Cooperative Crohn’s Disease Study. Gastroenterology. 1976 Mar;70(3):439-44. PMID: 1248701.
Needing a single index of degree of illness in Crohn’s disease, the National Cooperative Crohn’s Disease Study group collected data prospectively from 187 visits of 112 patients with Crohn’s disease of the small bowel, colon, or both. Information on 18 predictor variables was gathered at each visit. In addition, the attending physician rated his over-all evaluation of how well the patient was doing and compared the patient’s status with that at the previous visit. A multiple regression computer program was utilized to derive an equation for prediction of the physician’s over-all ratings from a subset of the predictor variables fulfilling a combination of constraints. This equation, numerically simplified and utilizing eight selected variabl […]