Low ALT Clinically Significant NAFLD Models




















The LACSNA (Low ALT Clinically Significant NAFLD) models are utilized to predict different histological phenotypes in patients with NAFLD and low ALT values.”


Formula :

See paper for formulas.

Explanation of Result :

For the possibility of cirrhosis, advanced fibrosis, NASH, and NASH with stage 2-3 fibrosis a prediction percentage is given.

Reference :

Gawrieh S, Wilson LA, Cummings OW, et al. Histologic Findings of Advanced Fibrosis and Cirrhosis in PatientsWith Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels. Am J Gastroenterol 2019;00:1–10.

* Please verify all calculations prior to clinical use.