The Fibrosis 4 score is a non-invasive scoring system based on several laboratory tests that help to estimate the amount of scarring in the liver. This score has been studied in liver disease due to Hepatitis C and NASH.
( Age x AST ) / ( Platelts x ( sqr ( ALT ) )
Explanation of Result :
For NASH : Fib4 score < 1.30 = F0-F1Fib4 score > 2.67 = F3-F4
For HCV with or without HIV : Fib4 score < 1.45 = F0-F1Fib4 score > 3.25 = F3-F4
- Kim BK1, Kim DY, Park JY, Ahn SH, Chon CY, Kim JK, Paik YH, Lee KS, Park YN, Han KH. Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients. Liver Int. 2010 Apr;30(4):546-53. PMID: 20074094.
- Shah AG1, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ; Nash Clinical Research Network. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2009 Oct;7(10):1104-12. PMID: 19523535.