APRI Index

[php]
// Pull in variables
if ($_POST) {
$a = $_POST[‘ast’];
$b = $_POST[‘ulnast’];
$c = $_POST[‘plt’];

// Do calculation
$var1 = $a / $b;
$var1 = $var1 * 100;
$var1 = $var1 / $c;
$result = round($var1, 2);

// write results
echo “Result : “;
echo $result . ” *”;

}

[/php]

Upper Limit of Normal AST :
AST :
Platelet Count :

[pullquote]The APRI is used to rule-out significant fibrosis and cirrhosis in Hep C and NAFLD.[/pullquote]
Formula :

[( AST / ULN AST ) x 100] / Platelets (109/L)]

Explanation of Result :

For NAFLD APRI values of < or = 0.3 and < or = 0.5 rule out significant fibrosis and cirrhosis, and a value of ≥ 1.5 rules in significant fibrosis. For Hepatitis C the ROC curves showed a concordance of 92% and 88.5% when 1.05 was the cut off (F3 and F4), and 87% and 83%, on 0.75 cut offs (F2-F4).”;

* Please verify all calculations prior to clinical use.